The Teenage Brain: A neuroscientist’s survival guide to raising adolescents and young adults. Frances Jensen E.
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СКАЧАТЬ National Monitoring the Future Study 1997–2011 by Mary A. Leonard, Biomedical Art and Design, University of Pennsylvania. Available at http://files.eric.ed.gov/fulltext/ED529133.pdf. B: Courtesy of Substance Abuse and Mental Health Services Administration, Department of Health and Human Services, National Treatment Episode Data Set 2007, adapted by Mary A. Leonard, Biomedical Art and Design, University of Pennsylvania. Available at http://www.samhsa.gov/data/DASIS/TEDS2k7AWeb/TEDS2k7AWeb.pdf). FIG. 22 Effects of Cannabinoids on Learning. (A: Reprinted by permission from Macmillan Publishers Ltd.: N. Stella et al., “A Second Endogenous Cannabinoid That Modulates Long-Term Potentiation,” Nature 388 [Aug. 21, 1997], 773–78, © 1997. B: Artwork by Mary A. Leonard, Biomedical Art and Design, University of Pennsylvania). FIG. 23 Long-Term Effects of Marijuana on Gray and White Matter in the Teen Brain. (A: Reprinted with permission from M. H. Meier et al., “Persistent Cannabis Users Show Neuropsychological Decline from Childhood to Midlife,” Proceedings of the National Academy of Sciences 109, no. 40 [Oct. 2, 2012], E2657–64, copyright 2012 National Academy of Sciences, U.S.A. B: Reprinted with permission from D. Arnone et al., “Corpus Callosum Damage in Heavy Marijuana Use: Preliminary Evidence from Diffusion Tensor Tractography and Tract-Based Spatial Statistics,” NeuroImage 41, no. 3 [July 1, 2008], 1067–74, © 2008, with permission from Elsevier). FIG. 24 Enhanced Effects of Cocaine on the Behavior of Adolescent Rats. (Reprinted from A.L. Wheeler et al., “Adolescent Cocaine Exposure Causes Enduring Macroscale Changes in Mouse Brain Structure,” Journal of Neuroscience 33, no. 5 [Jan. 30, 2013], 1797–1803a, with permission from Society for Neuroscience. Additional artwork by Mary A. Leonard, Biomedical Art and Design, University of Pennsylvania). FIG. 25 Stress Can Decrease Learning and LTP. (A, C: Artwork by Mary A. Leonard, Biomedical Art and Design, University of Pennsylvania. B: Created by the author, artwork by Mary A. Leonard, Biomedical Art and Design, University of Pennsylvania. D: Reprinted with permission from M. R. Foy et al., “Behavioral Stress Impairs Long-Term Potentiation in Rodent Hippocampus,” Behavioral and Neural Biology 48, no. 1 [July 1987], 138–49, © 1987, with permission from Elsevier. Additional artwork by Mary A. Leonard, Biomedical Art and Design, University of Pennsylvania). FIG. 26 Enhanced Response to Fearful Stimuli in Adolescents Compared with Children and Adults. (Reprinted from B. J. Casey et al., “Transitional and Translational Studies of Risk for Anxiety,” Depression and Anxiety 28, no. 1 [Jan. 2011], 18–28, © 2011 Wiley-Liss Inc.). FIG. 27 Prior Juvenile Diagnoses in Adults with Mental Disorders. (Reprinted from J. Kim-Cohen et al., “Prior Juvenile Diagnoses in Adults with Mental Disorder: Developmental Follow-Back of a Prospective-Longitudinal Cohort,” Archives of General Psychiatry 60, no. 7 [July 2003], 709–17, copyright © 2003 American Medical Association. All rights reserved). FIG. 28 Gender Differences in Brain Connections (Reprinted with permission from M. Ingalhalikar et al., “Sex Differences in the Structural Connectome of the Human Brain,” Proceedings of the National Academy of Sciences 111, no. 2 [Jan. 14, 2014], 823–28, copyright 2014 National Academy of Sciences, U.S.A.). FIG. 29 How Accountable Should Society Hold Adolescents? (Justice John Paul Stevens, United States Supreme Court; Steve Drizin, Northwestern University in Chicago; www.fairsentencingofyouth.org). FIG. 30 A Recap of Brain Development and the Critical Stage of Adolescence (Courtesy of the author).

       Introduction Being Teen

      What was he thinking?

      My beautiful, auburn-haired son had just returned home from a friend’s house with his hair dyed jet-black. Despite my inward panic, I said nothing.

      “I want to get red streaks in it,” he told me nonchalantly.

      I was gob-smacked. Is this really my child!? I’d begun to ask the question often during my fifteen-year-old son Andrew’s sophomore year at a private high school in Massachusetts, all the while trying to be empathetic. I was a divorced working mother of two teenage sons, putting in long hours as a clinician and professor at Boston Children’s Hospital and Harvard Medical School. So if I sometimes felt guilty about the time I spent away from my boys, I also was determined to be the best mother I could be. After all, I was a faculty member in a pediatric neurology department and actively researching brain development. Kids’ brains were my business.

      But my sweet-natured firstborn son had suddenly become unfamiliar, unpredictable, and bent on being different. He had just transferred from a very conventional middle school that went through ninth grade, where jackets and ties were the norm, to a very progressive high school. Upon arriving, he took full advantage of the new environment, and part of that was to dress in what you might describe as an “alternative” style. Let’s face it, his best friend had spiky blue hair. Need I say more?

      I took a deep breath and tried to calm myself. Getting mad at him, I knew, wouldn’t do either of us any good and probably would only alienate him further. At least he felt comfortable enough to tell me about something he wanted to do before he actually did it. This was an opportunity, I realized, and I quickly seized it.

      Instead of damaging your hair with some cheap, over-the-counter dye, what if I take you to my hair guy for the red streaks? I asked him. Since I also was going to pay for it, Andrew happily agreed. My hair stylist, who was a sort of punk rocker himself, got totally into the task. He did a great job, actually—so good that Andrew’s girlfriend at the time was inspired to color her hair in exactly the same black-and-red motif. She attempted this herself, and needless to say had different results.

      Thinking back to those days, I realize so much of what I thought I knew about my son during this turbulent time of his life seemed turned on its head. (Was that a compost pile in the middle of his bedroom, or laundry?) Andrew seemed trapped somewhere between childhood and adulthood, still in the grip of confusing emotions and impulsive behavior, but physically and intellectually more man than boy. He was experimenting with his identity, and the most basic element of his identity was his appearance. As his mother and a neurologist, I thought I knew everything there was to know about what was going on inside my teenager’s head. Clearly I did not. I certainly didn’t know what was going on outside his head either! So as a mother and a scientist, I decided I needed to—I had to—find out.

      Professionally, I was primarily studying the brains of babies at that time and running a research lab largely devoted to epilepsy and brain development. СКАЧАТЬ