Wheat Belly. William Davis, MD

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СКАЧАТЬ is therefore modern Triticum aestivum that, having been the focus of all manner of genetic shenanigans by geneticists, has accumulated substantial changes in genetically determined characteristics of gliadin and glutenin proteins within gluten. It is also the source for many of the other odd health phenomena experienced by consuming humans.

      In celiac disease, the one conventionally accepted (though miserably underdiagnosed) example of wheat-related intestinal illness, gliadin proteins, specifically α-gliadin, provoke an immune response that inflames the small intestine, causing abdominal cramps and diarrhea. Treatment is simple: complete avoidance of anything containing gluten. Unfortunately, this association has caused most people, including doctors, to believe that the only problem with wheat and grains is gluten when there are actually dozens of toxic compounds in the seeds of grasses.

      The “wheat is only a gluten problem” has blinded many people into thinking that, if you don’t have celiac disease, then eating all the ciabattas, donut holes, and tortellini you want is actually healthy. It has led to silly research efforts such as those conducted at Monash University in Australia in which purified gluten was administered to people with presumed non-celiac gluten intolerance and the majority (92 percent) tolerated it without gastrointestinal consequences, causing the authors to declare that gluten is not a problem for most people.¹⁸ Removing nicotine from cigarettes does not make smoking healthy. Tolerating purified gluten over a brief period of observation does not negate the potential for long-term harm, such as autoimmune diseases or brain effects, not to mention the harmful consequences of the dozens of other components besides gluten.

      Did you want a low-tar cigarette with that salami sandwich?

      IT’S NOT ALL ABOUT GLUTEN

      You now know that gluten isn’t the only potential villain lurking in wheat flour.

      Beyond gluten, the other 20 percent or so of non-gluten proteins in wheat include albumins, prolamins, and globulins, each of which can also vary from strain to strain. In total, there are more than a thousand other proteins that are meant to serve such functions as protecting the grain from pests, providing water resistance, and supplying reproductive functions. There are agglutinins, peroxidases, α-amylases, serpins, and acyl CoA oxidases, not to mention five forms of glyceraldehyde-3-phosphate dehydrogenases. I shouldn’t neglect to mention β-purothionin, puroindolines a and b, and starch synthases. Wheat ain’t just gluten, any more than southern cooking is just grits.

      Let’s take just one of these non-gluten proteins, wheat germ agglutinin, which has been enriched in modern strains of wheat through breeding to take advantage of its pest-resistant effects, making a stalk of wheat more resistant to fungi and molds. Wheat germ agglutinin is completely indigestible to humans, passing through the entire gastrointestinal tract unfazed by stomach acid, thumbing its nose at digestive enzymes and bile, eventually exiting into the toilet. But, in its travels from swallow to flush, it wreaks gastrointestinal havoc. One milligram (just a speck—there are 4,000 milligrams in just one packet of sugar) of purified wheat germ agglutinin fed to a laboratory animal results in extensive damage to the intestinal lining.¹⁹ While grains such as ancient wheat, rye, barley, and rice contain a single form of wheat germ agglutinin, modern wheat contains three different varieties, given its heightened genetic pliability. And this is just one protein among many beyond gluten in wheat and related grains.

      There are also allergic or anaphylactic (a severe allergic reaction resulting in shock) reactions to non-gluten proteins, including α-amylases, thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase, along with about a dozen others.²⁰ Exposure in susceptible individuals triggers asthma, rashes (eczema and hives), and a curious and dangerous condition called wheat-dependent exercise-induced anaphylaxis (WDEIA) in which rash, asthma, or anaphylaxis are provoked during exercise. WDEIA has been attributed to ω-gliadins and glutenins.

      Wheat and grains are rich in phytates, compounds that, like wheat germ agglutinin, provide pest-resistance to the plant. Once again, plant geneticists select strains richer in phytates and thereby are more pest-resistant. Phytate content parallels fiber content. This means that conventional advice to consume plentiful fiber from grains, such as whole grain breads and bran cereals hawked for promoting bowel regularity, thereby increases exposure to phytates. Problem: Phytates are effective binders of any mineral that has a positive charge. This includes iron, zinc, magnesium, and calcium. Phytates from grains are therefore a common cause of iron deficiency anemia, unresponsive to iron supplementation (since the iron never makes it to the bloodstream).^{21, 22} Zinc deficiency from phytates results in slowed wound healing, increased susceptibility to infections, skin rashes, impaired taste and smell, and slowed growth in children.²³ Wheat consumption is one of several causes of magnesium deficiency that is ubiquitous and results in bone thinning, higher blood pressure and blood sugar, muscle cramps, and heart rhythm disorders.²⁴ You may begin to appreciate just how many ironies there are in conventional diet advice: Eating more “healthy whole grains” to ensure adequate nutrition actually achieves the opposite.

      As if this protein/enzyme smorgasbord weren’t enough, food manufacturers have also turned to fungal enzymes, such as cellulases, glucoamylases, xylanases, and β-xylosidases, to enhance leavening and texture in wheat products. Many bakers also add soy flour to their dough to enhance mixing and whiteness, introducing yet another collection of proteins and enzymes. And farmers add their own unique collection of herbicides and pesticides such as glyphosate, imazamox, malathion, and chlorpyrifos. Choosing organic sources may reduce or eliminate exposure to such chemicals, but you’ve still got to contend with all the components intrinsic to the wheat plant.

      In short, wheat is not just a complex carbohydrate with gluten and bran. Wheat is a smorgasbord of compounds that vary widely according to genetic code. Just by looking at a poppy seed muffin, for instance, you would be unable to discern the variety of gliadins, wheat germ agglutinins, and other non-gluten proteins, phytates, and amylopectins contained within, much of it unique to modern semi-dwarf wheat. On taking your first bite, you might enjoy the immediate sweetness of the muffin’s amylopectin A, as it sends your blood sugar skyward, but you may be largely unaware of the toxic effects of its many other components until disaster strikes—in the form of pain and swelling caused by rheumatoid arthritis or stumbling and warm incontinence caused by cerebellar ataxia.

      Let’s next explore the incredible wide-ranging health effects of your muffin and other wheat-containing foods.

       PART TWO

       WHEAT AND ITS HEAD-TO-TOE DESTRUCTION OF HEALTH

       CHAPTER 4

       HEY, MAN, WANNA BUY SOME EXORPHINS? THE ADDICTIVE PROPERTIES OF WHEAT

      ADDICTION. WITHDRAWAL. DELUSIONS. Hallucinations. Wild, unrestrained outbursts. I’m not describing mental illness or a scene from One Flew Over the Cuckoo’s Nest. I’m talking about this food you invite into your kitchen, share with friends, and dunk in your coffee.

      I will discuss why wheat is unique among foods for its curious effects on the brain, effects shared with opiate drugs. It explains why some people experience incredible difficulty removing wheat from their diet. It’s not just a matter of inadequate resolve, inconvenience, or breaking well-worn habits; it’s about severing a relationship with something that gains hold of your psyche and emotions, not unlike the hold heroin has СКАЧАТЬ