Oil-in-Water Nanosized Emulsions for Drug Delivery and Targeting. Tamilvanan Shunmugaperumal

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       Library of Congress Cataloging‐in‐Publication Data

      Names: Shunmugaperumal, Tamilvanan, author.

      Title: Oil‐in‐water nanosized emulsions for drug delivery and targeting / Tamilvanan Shunmugaperumal.

      Description: First edition. | Hoboken : Wiley, [2021] | Includes bibliographical references and index.

      Identifiers: LCCN 2021019779 (print) | LCCN 2021019780 (ebook) | ISBN 9781119585220 (hardback) | ISBN 9781119585329 (adobe pdf) | ISBN 9781119585251 (epub)

      Subjects: LCSH: Drug delivery systems. | Emulsions. | Oils and fats–Solubility. | Nanomedicine.

      Classification: LCC RS199.5 .S58 2021 (print) | LCC RS199.5 (ebook) | DDC 615.1/9–dc23

      LC record available at https://lccn.loc.gov/2021019779 LC ebook record available at https://lccn.loc.gov/202101978

      Cover Design: Wiley

      Cover Image: Courtesy of Tamilvanan Shunmugaperumal

      I dedicate this book to my wife, Suriaprabha Marchen for her support, my son, Arunachalam Tamilvanan for his play‐time sacrifice with me, my director, Dr. USN Murty for his encouragement and sustained help, and all coauthors for their enthusiasm toward achieving the vision of this book.

      I dedicate this book to my father (late) Shunmugaperumal and mother Pethammal. I also dedicate this book to Prof. Simon Benita, School of Pharmacy, Hebrew University of Jerusalem, Israel.

LIST OF CONTRIBUTORS

      Abhinab Goswami, Research scholar, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India

      Oly Katari, Research scholar, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India

      Datta Maroti Pawde, Research scholar, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India

      Syed Nazrin Ruhina Rahman, Research scholar, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India

      Tamilvanan Shunmugaperumal, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India

FOREWORD

      It gives me an immense pleasure to write foreword for a book written by my colleague. This book provides comprehensive information concerning the oil‐in‐water nanosized emulsions as drug delivery carrier and drug targeting purpose. Very importantly, the generations of nanosized emulsions are updated according to the present‐day research focus, especially for reachable and unreachable organs/parts of the human body and thus, permitting the target place‐precised drug delivery and/or improved drug bioabsorption. A dedicated section covered in this book under heading, “Biofate of Nanosized Emulsions,” after their administration via different routes (dermal, nasal, ocular and parenteral) is a subject matter of interest for researchers. I strongly feel that this book will serve as a guide for formulation scientists working on oil‐in‐water nanosized emulsions in academic and industry levels.

      DR. USN MURTY

      Director

      National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India

PREFACE

      Over the years, so many new chemical entities (NCE) are constantly being discovered/designed/synthesized and even sometimes few NCE claim to be “molecular breakthrough” showing additional/exceptional better therapeutic activities in managing/treating single or multiple ailments. The so‐called molecular breakthrough NCE, in most of the times, are unable to provide the intended therapeutic application as they were thought initially. Thus, a question has come to find out the answer “why the sudden lacuna that prevents the successful development of NCE from laboratory to market (L‐to‐M).” In the present scenario, the L‐to‐M consists of multiple stages that include laboratory‐scale preformulation studies, systematic optimization of a formula to incorporate the NCE into the selected formulation, NCE‐incorporated formulation characterization and safety assessment at non/preclinical levels, clinical trials using the optimized СКАЧАТЬ