Man’s Thoughts are intent and fixed, wherever his Genius does naturally incline, and all his Aims and Application do continually tend, whether it be to pertinent or insignificant Matters; whether it be to useful, or else meerly curious Things; if he has but tolerable Parts, and Education corresponding, he can hardly ever miss; it is hardly possible he should miss the becoming Eminent, and in great Measure perfect, (I mean perfect (says he) according to the Modulum of Human Capacity) in that one Point. But there is one Thing to be recommended to the Consideration of the Person, who takes upon him the Enquiry into the Nature of one particular Disease, which perhaps he might be very liable to err in, if not cautioned against; and that is, that he be not too bold and rash in his Attempts; for, as Galen says, The Physician’s Art is not like that of an Artificer, who may make what Experiments he pleases, to satisfy his Curiosity; because if he spoils the Materials he works on, no Body is endangered by the Miscarriage: In Corpore autem humane (adds he) ea tentare quæ non sunt Experientium comprobata Periculo non vacat, cum temerariæ Experientiæ Finis sit totius Animantis internecio. I believe we shall find that one of the grand Reasons, why Persons, generally speaking, have been so negligent in making any Attempts on Cancers, has been the seeming Discouragement they have all along met with from Authors. The Caution Hypocrates has given us in his Thirty eighth Aphor. Sect. 6. has scarce been omitted by any one considerable Person that has wrote of this Subject, tho’ perhaps the Sentence has often had an Exposition put upon it, contrary to the Author’s Meaning; but of this, more in it’s proper Place. I proceed now to give an Idea of Cancers in the Breast from an external Cause; and this I shall do without concerning my self with the Opinion of the Ancients; for since we have been so happy as to live in an Age which will be remarkable for the many surprising Discoveries which have been made in Anatomy: We should be reckoned unworthy the Advantages we enjoy, if we did not study to apply them to the Benefit of Mankind in general. The more inquisitive and learned Part of the World, are at this time very well assured that the Animal Body is an exquisitely framed Machine, and that it’s Composure is little else than a Compages of branching and winding Canals, which are kept to a moderate Degree of Extention, by Fluids of different Natures; and that the Motions of these were first determined by the divine Architect: Thus in a natural State, the whole Fabrick is governed by certain Laws impressed on the Fluids; and we often find the unhappy Consequences of the Discomposure of a Part, to discover themselves first by an Interruption of the Motion of the animal Juices. Thus in a Cancer of the Breast which proceeds from a Blow or Bruise (as upon strict Enquiry we have found they most commonly do) is it not probable that by such means a Confusion of the true Order of the little Glandulous Grains and their excretory Ducts may happen? and at the same time an extravasated Lympha may lodge in such a spungy Texture, which in time becoming viscid, will coalesce with the Glandular Substance, and form a Mass considerably compact? Now this being so, it is reasonable to believe that as the Lymphatic Juice continues its Motion till it arrives at the indurated Part, its Passage must be embarrassed there; upon which, it will soon be qualified for an Union with the remaining Part of the glandulous Substance of the Breast; and so the whole be perfectly changed from what it was before. This Hypothesis is in a great Measure grounded on Experiments; for if we express a Juice from some of the Cancerous Mass, and hold some of it in a Spoon over a Fire, there immediately flys off a small Vapour, and the Remainder hardens not unlike the white of an Egg boiled; this shows it to have the Properties of the Lympha; for the Chymical Analysis of that Liquor assures us it is a Composition of a great deal of fixt Sulphur, a little Volatile, some Phlegm, and much Volatile Alkalie; to which some add a little Earth: Now while the Volatile Alkalie keeps the Sulphur dissolved, the Lympha remains in a State of Fluidity; but when, by making the same Experiment, the Volatile Alkalie is evaporated, the Remainder hardens, and forms a pretty compact, whitish Substance. From hence the judicious SURGEON may easily deduce the Reason why these Sort of Tumours can never be brought to Suppuration. We shall not be so particular as to mention those Cancers which proceed from internal Causes, nor several other things which relate to the former; for what we have here said, we look upon to be commonly the Method of the Formation of them; and as such, we did endeavour to calculate Remedies that should peculiarly operate on the Mass, so as to dis-unite the firm Cohæsion of its Parts, and dispose them to separate and come away, without any great Inconvenience to the Patient; which is what we would recommend with all the Earnestness imaginable to those that are desirous of discovering a Method of curing Cancers. We were before sensible that it was possible for one Body to operate on another determinate Body, without being able to have any such Effect on innumerable Others; as Quicksilver will desolve Gold, Aqua-fortis Iron, Vinegar the Shell of an Egg, Oyl common Sulphur, &c. which will not have any such Effect on several other Bodies; for there is nothing more certain than that the Operations of Dissolvents are so determined by the various Texture of the Bodies on which they are employed, that a Liquor that is capable to corrode a more hard and solid Body, may be unable to disunite the Parts of one more soft and thin, if of a Texture indisposed to admit the small Parts of the Menstruum. It may be expected I should say something in relation to that which is generally looked upon to be the grand Cause of the Incurableness of Cancers, I mean the acid Humour in the Blood. But if those Gentlemen who are fond of entertaining this Opinion, do but consider that Cancers are often formed in a perfect State of Health; and that during the Time the Cancerous Substance dissolves, and comes away according to our Method, the Sides will run a digested Matter, and heal by the Application of dry Lint only; they will be of my Opinion, that neither the Atrabile of the Ancients, the corrosive Alkalious Salt of the Chymists, nor the predominant Acid of the Rest of the Moderns, are capable of procuring those Alterations that Cancers are sometimes attended with. If we trace the Writings of our Predecessors to their earliest Date, we shall find that many of them have made Mention of the Roots of the Cancer, which they took to be the large blew Veins that are often extended on its Surface; and the entire Removal of these they thought to be absolutely necessary, or the Patient could not be cured: But I believe there is no Body at this Time that considers the Mechanism of the Parts in such a Condition, but will agree they are the necessary Consequents of it, and that their Absence, or Presence is of no Importance; that the Cancer is sometimes attended with Adherents, or Appendices, which may very well resemble Roots, we are assured; but these generally lay deep, and not easily discovered; the most considerable One that ever we saw was very near Five Inches long, and of an unequal Bigness, some Part of it did not exceed the Largeness of a Goose’s Quill, but some others were near as big as the Top of the Thumb, which resembled so many Knots in it, it divided in the Middle, and continued separated about an Inch and a Half, and then re-united, it was of a more tender Substance than the Body of the Cancerous Mass, but of the same Colour, and was probably the Juice that was last applied to the Cancer, which assumed a Form agreeable to the Cavities it lodged it self in. Such Adherents as these are, I am more inclined to believe, are the Cause of the unsuccessful Attempts on Cancers, than any Acid in the Blood; for I am of opinion there are few Persons unacquainted with Medicines that are capable of correcting its Acidity when it happens; and had the Cure of Cancers depended on that, I am positive they would not at this Time have had such ill Character. We have before shewed that Cancers have generally their Rise from a Blow or Bruise, and that when the Body is in an healthful Condition, and the Blood and Lympha temperate and sweet: Now if there always is an Acidity of the Blood when Persons are afflicted with Cancers, the Cancers must sometimes cause it, and not the Acid in the Blood the Cancers, as is the Opinion of most of the Moderns. What has been hitherto said, is sufficient to prove that if Men will be always so sluggish as to acquiesce in the Dictates and Dogmatical Positions of their Predecessors, and not exert their Faculties in endeavouring to undeceive themselves; we must no longer expect our Art will receive any Advancements, but as Slaves to their Opinions content our selves with what we know already. Were not Parisani, Riolan the Son, and Plempius, so much in the Interest of the Ancients, that when our Country-man, the assiduous Harvey, had discovered the Circulation of the Blood, they not only opposed his plain Demonstrations, but engaged in vigorous Disputes against him, tho’ at the last they were obliged shamefully to recant their Follies. Celsus tells us, Vix ulla perpetua Præcepta Ars Medicinalis recipit;
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