See Origin of Species, pp. 5-8. "Changed conditions induce an almost indefinite amount of fluctuating variability, by which the whole organization is rendered in some degree plastic" (Descent of Man, p. 30). It also appears that "the nature of the conditions is of subordinate importance in comparison with the nature of the organism in determining each particular form of variation; – perhaps of not more importance than the nature of the spark, by which a mass of combustible matter is ignited, has in determining the nature of the flames" (Origin of Species, p. 8).