Antibody-Drug Conjugates. Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer. Sara A. Hurvitz

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Название: Antibody-Drug Conjugates. Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer

Автор: Sara A. Hurvitz

Издательство: John Wiley & Sons Limited

Жанр: Медицина

Серия:

isbn: 9781119060840

isbn: 0

Аннотация:

Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development