Genome Editing in Drug Discovery. Группа авторов

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СКАЧАТЬ screening for cell cycle regulators using arrayed synthetic crRNA libraries. J. Biotechnol. 251: 189–200.

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      76 Takeda, H., Kataoka, S., Nakayama, M. et al. (2019). CRISPR‐Cas9‐mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes. Proc. Natl. Acad. Sci. U. S. A. 116: 15635–15644.

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      78 Tuladhar, R., Yeu, Y., Tyler Piazza, J. et al. (2019). CRISPR‐Cas9‐based mutagenesis frequently provokes on‐target mRNA misregulation. Nat. Commun. 10: 4056.

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      84 Wienert, B., Wyman, S.K., Richardson, C.D. et al. (2019). Unbiased detection of CRISPR off‐targets in vivo using DISCOVER‐Seq. Science 364: 286–289.

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      90 Zetsche, B., Gootenberg, J.S., Abudayyeh, O.O. et al. (2015). Cpf1 is a single RNA‐guided endonuclease of a class 2 CRISPR‐Cas system. Cell 163: 759–771.

      91 Zhang, F. (2019). Development of CRISPR‐Cas systems for genome editing and beyond. Q. Rev. Biophys. 52: 1–31.

      92 Zhao, Y., Tyrishkin, K., Sjaarda, C. et al. (2019). A one‐step tRNA‐CRISPR system for genome‐wide genetic interaction mapping in mammalian cells. Sci. Rep. 9: 14499.

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