Pathology of Genetically Engineered and Other Mutant Mice. Группа авторов

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      1 Chapter 2Table 2.1 Websites with information useful for phenotyping mutant laborator...Table 2.2 SNP comparison between inbred strains for the Abcc6 gene. A search of t...Table 2.3 Polymorphisms in Adh7. Two SNP in the Adh7 gene (formerly called Adh4) ...Table 2.4 Sources of mouse models for human diseases.

      2 Chapter 3Table 3.1 Types of mouse strains.Table 3.2 Standardized nomenclature.Table 3.3 Inbred strains of mice.Table 3.4 Inbred strain nomenclature.Table 3.5 Examples of inbred strain abbreviations.Table 3.6 F1 and F2 hybrid mice.Table 3.7 Breeding data used to identify the gene responsible for the hair ...Table 3.8 Recombinant inbred and recombinant congenic strain designation.Table 3.9 Congenic strains.Table 3.10 Outbred mouse stocks.Table 3.11 Evolution of the nomenclature for nude.Table 3.12 Nomenclature for spontaneous mouse mutations.Table 3.13 Nomenclature for transgenic mice.

      3 Chapter 4Table 4.1 Criteria for accurately defining an animal model, regardless of h...

      4 Chapter 5Table 5.1 Common embryonic or neonatal defects leading to lethality.Table 5.2 Common placental defects leading to embryonic lethality.

      5 Chapter 7Table 7.1 Defects in thymus development in genetically engineered mice.Table 7.2 Defects in the development of secondary lymphoid tissues in genet...

      6 Chapter 8Table 8.1 Myeloid leukemia associated with conventional mice and mouse mode...Table 8.2 Nonlymphoid hematopoietic sarcomas associated with conventional m...Table 8.3 B‐cell lymphoid neoplasms associated with conventional mice and m...Table 8.4 T‐cell lymphoid neoplasms associated with conventional mice and m...

      7 Chapter 9Table 9.1 Common genetic mutations in immunodeficient strains used in biome...Table 9.2 A comparison of advantages and disadvantages offered by PDX model...Table 9.3 Clostridioides difficile‐induced lesions in different mouse strains.Table 9.4 Historically recognized pathogens – effects in immunodeficient mo...Table 9.5 Neoplastic, degenerative, and miscellaneous lesions in immunodefi...

      8 Chapter 10Table 10.1 Functions of the skin.Table 10.2 Comparisons of structures and functions of skin and adnexa betwe...Table 10.3 Classification of primary scarring (cicatricial) alopecias.Table 10.4 Human ichthyosiform dermatoses and mouse orthologs.Table 10.5 Nonmelanoma skin cancers in mice by induction method.Table 10.6 Mouse models for the various forms of human Epidermolysis Bullos...

      9 Chapter 11Table 11.1 Breast cancer genes and mouse models.

      10 Chapter 12Table 12.1 Antibodies used to evaluate mouse lung by immunohistochemistry i...Table 12.2 Examples of genetic based human lung diseases for which mouse mo...Table 12.3 Examples of mouse genes that when mutated create models for gene...Table 12.4 Examples of lung tumors from targeting single or combined driver...Table 12.5 Classification of proliferative lung lesions of mice.

      11 Chapter 13Table 13.1 Examples of mouse models of heritable and non‐heritable human ga...Table 13.2 Role of genes in enteritis and colitis in humans and mice.Table 13.3 Common molecular pathways in human colorectal carcinogenesis.Table 13.4 Examples of mouse models of human heritable cancer syndromes ass...Table 13.5 Nomenclature of mouse glandular stomach and intestinal epithelia...Table 13.6 Features helpful in distinguishing invasive adenocarcinoma from ...

      12 Chapter 14Table 14.1 Immunohistochemical markers useful for evaluating the cardiovasc...Table 14.2 Genetically engineered mice (GEMs) models of heart disease: revi...Table 14.3 Genes that have been engineered in mice to produce models of vas...

      13 Chapter 15Table 15.1 Mouse liver immunohistochemistry.Table 15.2 Relevant GEM models for human nonneoplastic liver diseases.Table 15.3 Relevant GEM models for human neoplastic liver diseases.Table 15.4 Most commonly diagnosed hepatic proliferative lesions found in m...Table 15.5 Useful immunohistochemical markers and their reactivity in diffe...Table 15.6 Major genetic alterations, their type of mutation, and their occ...Table 15.7 Mouse models of human hereditary pancreatitis.Table 15.8 Common genes used to drive expression in genetic models of exocr...Table 15.9 Classification and grading of mouse and human pancreatic intradu...Table 15.10 Human pancreatic cancer genetics and mouse models of human PDAC...

      14 Chapter 16Table 16.1 Mouse models: neurogenic myopathies.Table 16.2 Mouse models: myogenic myopathies.

      15 Chapter СКАЧАТЬ