Pathology of Genetically Engineered and Other Mutant Mice. Группа авторов
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Название: Pathology of Genetically Engineered and Other Mutant Mice

Автор: Группа авторов

Издательство: John Wiley & Sons Limited

Жанр: Биология

Серия:

isbn: 9781119624592

isbn:

СКАЧАТЬ https://www.alliancegenome.org Identification of animal models for human disease Atlas of mouse cardiovascular development https://www.devbio.pitt.edu/research/atlas‐mouse‐cardiovascular‐development Atlas of the mouse cardiovascular system using EFIC Bonebase http://www.bonebase.org Variation in bone mass using μCT and histomorphometry for KOMP mice Emouseatlas https://www.emouseatlas.org/emap/home.html Mouse embryonic anatomy and development GUDMAP https://www.gudmap.org Urogenital and prostate development with a collection of immunohistochemical, histological, and immunofluorescence images, and gene expression data International Mouse Phenotyping Consortium (IMPC) https://www.mousephenotype.org Summaries of phenotyping of genetically engineered mice in the KOMP program Monarch https://monarchinitiative.org Identification of animal models for human disease Mouse Brain Atlas https://developingmouse.brain‐map.org, https://mouse.brain‐map.org High‐resolution physical atlases of the adult and embryonic mouse brains Mouse Genome Informatics http://www.informatics.jax.org Large datasets on mice, genetics, inbred strains, mutant lines, etc. Mouse Genome Informatics SNP Database http://www.informatics.jax.org/snp Single nucleotide polymorphisms for inbred strains MouseMine http://www.mousemine.org/mousemine/begin.do Comparative human and mouse data Mouse Models of Human Cancer Database (MMHCD) http://tumor.informatics.jax.org/mtbwi/index.do Mouse models of human cancer data and images Mouse Phenome Database https://phenome.jax.org Variety of data on studies that compare inbred strains MUTAGENETIX https://mutagenetix.utsouthwestern.edu Immunological phenotypes of single gene mouse mutants produced by ENU mutagenesis National Toxicology Program Neoplastic Lesion Atlas https://ntp.niehs.nih.gov/nnl/index.htm Atlas of images and descriptions on nonneoplastic lesions in rats and mice Noah's Arkive http://noahsarkive.cldavis.org/cgi‐bin/show_image_info_page.cgi Images of lesions from many different species Online Mendelian Inheritance in Man (OMIM) https://www.ncbi.nlm.nih.gov/omim Summaries with references on genetic based diseases in humans with reference to animal models Pathbase, The European Mouse Pathology Database http://www.pathbase.net Images of lesions found in mice (spontaneous, genetically engineered, etc.) PATHBIO http://www.pathbio.org Training modules, X‐ray atlas, lymphatic mapping atlas, images of inbred strain specific diseases Sanger Mouse SNP Database https://www.sanger.ac.uk/sanger/Mouse_SnpViewer/rel‐1505 Single nucleotide polymorphisms for 36 inbred strains Skinbase http://eulep.pdn.cam.ac.uk/~skinbase/index.php Subdirectory of Pathbase focusing on normal and abnormal skin phenotypes in mice

      Many archival databases and some reference resources are very dependent on users to curate, correct uploads, and to give them added value for a community. Databases run for the use of specific communities can provide a high degree of added value at low cost and contribute heavily to scientific sustainability. Image databases especially fall into this category and in particular need new material from experts in the field to constantly expand the resource and accurately curate the material. Pathologists can use these resources as legacy tools for extra photomicrographs they take while working up new models or defining spontaneous diseases in colonies. Such additional images can be referenced in the primary publication as being publicly available on the websites, which usually is very well received by journals and reviewers on future grant applications. Many of the current public repositories will not accept files of the size of zoomable histopathology images and limited user uploads. This, together with payment to commercial repositories is a specific problem for very image intensive histopathology and cell biology data.

      Mouse Genome Informatics (http://www.informatics.jax.org)

      The Mouse Genome Informatics (MGI) international СКАЧАТЬ